Pädiatrie up2date, Inhaltsverzeichnis Pädiatrie up2date 2015; 10(02): 179-192DOI: 10.1055/s-0034-1391977 Hämatologie/Onkologie © Georg Thieme Verlag KG Stuttgart · New YorkEisenmangelanämie und Eisenstoffwechselstörungen Stefan W. Eber , Lena A. MachetanzArtikel empfehlen Abstract Artikel einzeln kaufen Alle Artikel dieser Rubrik Volltext Referenzen Literatur 1 Halterman JS, Kaczorowski JM, Aligne CA et al. Iron Deficiency and Cognitive Achievement Among School-Aged Children and Adolescents in the United States. Pediatrics 2001; 107: 1381-1386 2 Aggett PJ, Agostoni C, Axelsson I et al. Iron metabolism and requirements in early childhood: do we know enough? a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2002; 34 : 337-345 3 Iolascon A, De Falco L, Beaumont C. Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis. Haematologica 2009; 94 : 395-408 4 Muckenthaler MU. Fine Tuning of Hepcidin Expression by Positive and Negative Regulators. Cell Metabolism 2008; 8: 1-3 5 Du X, She E, Gelbart T et al. The serine protease TMPRSS6 is required to sense iron deficiency. Science 2008; 320: 1088-1092 6 Andrews NC. Forging a field: the golden age of iron biology. Blood 2008; 15: 219-230 7 Guillem F, Lawson S, Kannengiesser C et al. Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anaemia and iron deficiency. Blood 2009; 113 : 5605-5608 8 Behnisch W, Muckenthaler M, Kulozik A. Eisenmangelanämie. http://www.awmf.org/leitlinien/detail/ll/025-021.html 9 Kulozik AE, Kunz J. Anämiediagnostik im Kindesalter. Leitlinie der Gesellschaft für pädiatrische Onkologie und Hämatologie. http://www.awmf.org/leitlinien/detail/ll/025-027.html 10 Van Wyck DB, Mangione A, Morrison J et al. BLOOD MANAGEMENT: Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial. Transfusion 2009; 49: 2719-2728 11 Bansal D et al. Serodiagnosis of celiac disease in children referred for evaluation of anemia: a pediatric hematology unit’s experience. Indian J Pathol Microbiol 2011; 54: 756-760 12 Husby S, Koletzko S, Korponay-Szabo IR et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. Guidelines for the Diagnostik of Coeliac Disease. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition; 2012 13 Von Schenk U, Bender-Götze C, Koletzko B. Persistence of neurological damage induced by dietary vitamin B-12 deficiency in infancy. Archives of Disease in Childhood 1997; 77: 137-139 14 Korenke CG, Hunneman DH, Eber SW et al. Severe encephalopathy with epilepsy in an infant caused by subclinical maternal pernicious anemia. Case report and review of the literature. Eur J Pediatr 2004; 163: 196-201 (Review: Eur J Pediatr 2004; 163 (4 – 5): 207 – 209) 15 Burdach S. Schwerpunktthema Anämie. Monatsschrift Kinderheilkunde Heft 1/2015 16 Finberg KE, Heeney MM, Champagna DR et al. Mutations in the TMPRSS6 cause iron refractory iron deficiency (IRIDA). Nat Genet 2008; 40: 569-571 17 Preza G, Ganz T, Nemeth E et al. Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. J Clin Invest 2011; 121: 4880-4888 18 Malekzadeh MM, Radmard AR, Nouroozi A et al. Juvenile Hemochromatosis, Genetic Study and Long-term Follow up after Therapy. Middle East J Digest Disease 2014; 6: 87-92 19 Cario H et al. Leitlinie: Cario H et al. Diagnostik und Therapie der sekundären Eisenüberladung bei Patienten mit angeborenen Anämien. http://www.awmf.org/uploads/tx_szleitlinien/025-029l.pdf 20 Cappellini MD, Cohen A, Piga A et al. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia. Blood 2006; 107: 3455-3462 21 Wonke B, Wright C, Hoffbrand AV. Combined therapy with deferiprone and desferrioxamine. Brit J Haematol 1998; 103: 361-364